However, acyclovir-or ganciclovir-resistant mutants with alterations in viral DNA polymerase may also be resistant to foscarnet.
2.
The mechanism for this specificity is unknown, but drug-resistant mutants cluster in regions around the active site.
3.
When all goes well, the drugs hold reproduction of the virus so low that no resistant mutants can evolve.
4.
Antibiotics create a selective pressure by killing off weak bacteria and allowing the stronger, resistant mutant germs to survive.
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:: : Can hand sanitizers breed resistant mutants like antibiotics do ? talk ) 23 : 57, 26 February 2008 ( UTC)
6.
A case study of an irradiated " Escherichia coli " population found a growing number of bacteriophage-resistant mutants induced by the light.
7.
They isolated rapamycin-resistant mutants of " Saccharomyces cerevisiae " and discovered that mutations in any of three genes can confer rapamycin resistance.
8.
Triclosan has been employed as a transformed by a plasmid harboring a triclosan-resistant mutant " FabI " gene ( mFabI ) as a selectable marker can grow in presence of high dose of triclosan in growth media.
9.
With Michael Klein, Robert Lamb and Larry Pinto, DeGrado extensively characterized the physiological properties of many drug-resistant mutants of the channel, identified those most likely to lead to resistance, and designed new drugs to address the problem of drug-resistant forms of influenza A virus.
10.
When cells are induced to undergo apoptosis, caspase 3 cleaves ICAD to dissociate the CAD : ICAD complex, allowing CAD to cleave chromosomal DNA . Cells that lack ICAD or that express caspase-resistant mutant ICAD thus do not show DNA fragmentation during apoptosis, although they do exhibit some other features of apoptosis and die.
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